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Symbol Name ID |
Foxa2
forkhead box A2 MGI:1347476 |
| Darker colors indicate more annotations |
| Mouse Phenotypes | pulmonary vascular congestion |
respiratory system inflammation |
impaired lung alveolus development |
abnormal lung saccule morphology |
abnormal pulmonary alveolus epithelial cell morphology |
absent type I pneumocytes |
abnormal type II pneumocyte morphology |
absent alveolar lamellar bodies |
abnormal pulmonary alveolus wall morphology |
atelectasis |
dilated respiratory conducting tube |
pulmonary hyaline membrane formation |
abnormal respiratory mucosa goblet cell morphology |
increased respiratory mucosa goblet cell number |
increased airway resistance |
respiratory distress |
abnormal respiratory mechanics |
decreased lung compliance |
abnormal surfactant composition |
abnormal surfactant secretion |
decreased surfactant secretion |
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| Availability | Mouse Genotype | |||||||||||||||||||||
| Foxa2tm1.1Khk/Foxa2+ | ||||||||||||||||||||||
| Foxa2tm1Khk/Foxa2tm1Khk Tg(SFTPC-rtTA)5Jaw/0 Tg(tetO-cre)1Jaw/0 (conditional) |
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| Foxa2tm1Khk/Foxa2tm1Khk Tg(Scgb1a1-rtTA)1Jaw/0 Tg(tetO-cre)1Jaw/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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